To examine rates of Shigella infections in household contacts of pediatric shigellosis patients, we followed contacts and controls prospectively for 1 week after the index patient obtained care.
Household contacts of patients were 44 times more likely to develop a Shigella infection than were control contacts (odds ratio 44.7, 95% CI 5.5Ė361.6); 29 (94%) household contacts of shigellosis patients were infected with the same species and serotype as the index patientís.
Pulsed-field gel electrophoresis showed that 14 (88%) of 16 with infected contacts had strains that were indistinguishable from or closely related to the index patientís strain.
Latrine area fly counts were higher in patient households compared with control households, and 2 patient household water samples were positive for Shigella.
We show high susceptibility of household contacts of shigellosis patients to Shigella infections and found environmental risk factors to be targeted in future interventions.
Emerging Infectious Diseases, Vol. 21, No. 11, November 2015